Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11506450 | 1.00 | TSHR (0.44) | TSHRALDH1A1MAPTUSP2CYP3A4 | |
| SCHEMBL3119019 | 1.00 | TSHR (0.44) | TSHRALDH1A1MAPTUSP2CYP3A4 | |
| SCHEMBL3126461 | 1.00 | TSHR (0.44) | TSHRALDH1A1MAPTUSP2CYP3A4 | |
| SCHEMBL3118685 | 1.00 | TSHR (0.44) | TSHRALDH1A1MAPTUSP2CYP3A4 | |
| SCHEMBL3126386 | 1.00 | TSHR (0.44) | TSHRALDH1A1MAPTUSP2CYP3A4 | |
| SCHEMBL3123538 | 0.98 | TSHR (0.41) | TSHRALDH1A1MAPTUSP2CYP3A4 | |
| SCHEMBL3118274 | 0.91 | — | — | |
| SCHEMBL3446959 | 0.91 | — | — | |
| Undecanal SCHEMBL8210493 | 0.88 | TSHR (0.53) | TSHRALDH1A1MAPTUSP2CYP3A4 | |
| SCHEMBL11219471 | 0.83 | TSHR (0.56) | TSHRALDH1A1MAPTSMN1; SMN2ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782638-A1 | STAPLED AND STITCHED POLYPEPTIDES AND USES THEREOF | President and Fellows of Harvard College (US) | 2021-02-24 | — | — | EP | disclosed |