Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2305943 | 1.00 | CDK4 (0.84) | CDK4CDK1 | |
| SCHEMBL2301937 | 1.00 | CDK4 (0.84) | CDK4CDK1 | |
| SCHEMBL2300646 | 0.91 | CDK4 (1.00) | CDK4CDK1 | |
| SCHEMBL12426776 | 0.91 | CDK4 (1.00) | CDK4CDK1 | |
| SCHEMBL15032366 | 0.91 | CDK4 (1.00) | CDK4CDK1 | |
| SCHEMBL2303577 | 0.91 | CDK4 (1.00) | CDK4CDK1 | |
| SCHEMBL2298681 | 0.91 | CDK4 (1.00) | CDK4CDK1 | |
| SCHEMBL2363949 | 0.83 | CDK4 (0.83) | CDK4CDK1 | |
| SCHEMBL2303440 | 0.81 | CDK4 (0.85) | CDK4CDK1 | |
| SCHEMBL15032346 | 0.80 | CDK4 (0.77) | CDK4CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536730-A1 | PYRROLOPYRIMIDINE COMPOUNDS AS INHIBITORS OF CDK4/6 | Novartis AG (CH) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011101409-A1 | PYRROLOPYRIMIDINE COMPOUNDS AS INHIBITORS OF CDK4/6 | NOVARTIS AG (CH) | 2011-08-25 | — | — | WO | disclosed |