Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23020074 | 1.00 | PIM1 (0.45) | PIM1CYP1A2ALDH1A1CYP3A4MEN1 | |
| SCHEMBL23020119 | 0.94 | PIM1 (0.47) | PIM1CYP1A2ALDH1A1CYP3A4MEN1 | |
| SCHEMBL23020066 | 0.89 | CYP1A2 (0.43) | PIM1CYP1A2ALDH1A1CYP3A4MEN1 | |
| SCHEMBL19939355 | 0.89 | CYP1A2 (0.44) | PIM1CYP1A2ALDH1A1CYP3A4MEN1 | |
| SCHEMBL19942104 | 0.89 | CYP1A2 (0.44) | PIM1CYP1A2ALDH1A1CYP3A4MEN1 | |
| SCHEMBL23020310 | 0.89 | PIM1 (0.43) | PIM1CYP1A2ALDH1A1CYP3A4MEN1 | |
| SCHEMBL23020116 | 0.88 | MEN1 (0.40) | PIM1CYP1A2ALDH1A1CYP3A4MEN1 | |
| SCHEMBL23020068 | 0.88 | MEN1 (0.40) | PIM1CYP1A2ALDH1A1CYP3A4MEN1 | |
| SCHEMBL19939354 | 0.88 | CYP1A2 (0.43) | PIM1CYP1A2ALDH1A1CYP3A4MEN1 | |
| SCHEMBL19942211 | 0.88 | CYP1A2 (0.43) | PIM1CYP1A2ALDH1A1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3392242-B1 | NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME | LG CHEMICAL LTD (KR) | 2021-02-24 | — | — | EP | disclosed |