Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL7115951 | 1.00 | — | — | |
| Bicarbonate SCHEMBL18989584 | 0.94 | CA4 (0.55) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL28267792 | 0.94 | — | — | |
| Bicarbonate SCHEMBL7148687 | 0.94 | — | — | |
| Bicarbonate SCHEMBL28963761 | 0.94 | — | — | |
| Bicarbonate SCHEMBL28858591 | 0.94 | — | — | |
| Bicarbonate SCHEMBL5072811 | 0.94 | — | — | |
| Bicarbonate SCHEMBL28139628 | 0.94 | — | — | |
| Bicarbonate SCHEMBL1331961 | 0.94 | — | — | |
| Bicarbonate SCHEMBL3266233 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028634-B1 | CALCIUM COMPLEXES FOR FORTIFICATION OF FOODS | NESTLE SA (CH) | 2003-04-09 | — | — | EP | claimed |
| US-6024994-A | CALCIUM COMPLEXES AND EMULSIFIERS FOR FOODS | NESTEC S.A. (CH) | 2000-02-15 | — | — | US | claimed |
| US-20150005466-A1 | AB BLOCK COPOLYMER DISPERSANTS HAVING AN INK VEHICLE SOLUBLE BLOCK | DU PONT (US) | 2015-01-01 | — | — | US | disclosed |
| US-8500266-B2 | AB block copolymer dispersants having an ink vehicle soluble block | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-08-06 | — | — | US | disclosed |
| US-20110199420-A1 | AB BLOCK COPOLYMER DISPERSANTS HAVING AN INK VEHICLE SOLUBLE BLOCK | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2011-08-18 | — | — | US | disclosed |
| US-4731265-A | Method of manufacturing modified wood material | MATSUSHITA ELECTRIC WORKS, LTD. (JP) | 1988-03-15 | — | — | US | disclosed |