⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10465162 | 1.00 | — | — | |
| SCHEMBL20853060 | 0.78 | — | — | |
| SCHEMBL10465603 | 0.72 | NPC1 (0.36) | — | |
| SCHEMBL21558183 | 0.72 | TDP1 (0.39) | — | |
| SCHEMBL19343655 | 0.69 | — | — | |
| SCHEMBL6518837 | 0.69 | — | — | |
| SCHEMBL22142906 | 0.69 | — | — | |
| SCHEMBL21894241 | 0.69 | — | — | |
| SCHEMBL17080725 | 0.69 | — | — | |
| SCHEMBL18903786 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912699-B2 | Tau-protein targeting compounds and associated | ARVINAS OPERATIONS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |
| US-20210054466-A1 | TUMOR BIOMARKERS AND USE THEREOF | CUREGENIX CORPORATION | 2021-02-25 | — | — | US | disclosed |