⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698783 | 0.80 | TSHR (0.43) | — | |
| SCHEMBL10936380 | 0.75 | TSHR (0.40) | — | |
| SCHEMBL31426785 | 0.73 | TSHR (0.39) | — | |
| SCHEMBL3214992 | 0.73 | — | — | |
| SCHEMBL23720674 | 0.72 | TSHR (0.31) | — | |
| SCHEMBL8119138 | 0.72 | — | — | |
| SCHEMBL19959733 | 0.71 | — | — | |
| SCHEMBL5168007 | 0.70 | — | — | |
| SCHEMBL8750865 | 0.68 | TSHR (0.34) | — | |
| SCHEMBL8750877 | 0.68 | TSHR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112020507-B | Amide compound and method for producing polynucleotide using same | 住友化学株式会社 | 2023-10-10 | — | — | CN | disclosed |
| US-20210238217-A1 | AMIDITE COMPOUND AND METHOD FOR PRODUCING POLYNUCLEOTIDE USING SAID COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-08-05 | — | — | US | disclosed |
| EP-3786173-A1 | AMIDITE COMPOUND AND METHOD FOR PRODUCING POLYNUCLEOTIDE USING SAID COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2021-03-03 | — | — | EP | disclosed |
| CN-112020507-A | Amide compound and method for producing polynucleotide using same | 住友化学株式会社 | 2020-12-01 | — | — | CN | disclosed |