⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294750 | 0.78 | — | — | |
| SCHEMBL2473114 | 0.75 | — | — | |
| SCHEMBL5003747 | 0.73 | — | — | |
| SCHEMBL8533026 | 0.73 | KMT2A (0.67) | — | |
| SCHEMBL599653 | 0.73 | — | — | |
| SCHEMBL9642477 | 0.73 | — | — | |
| SCHEMBL30464064 | 0.71 | — | — | |
| SCHEMBL768028 | 0.71 | — | — | |
| SCHEMBL3313676 | 0.71 | — | — | |
| SCHEMBL1109097 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181280-B2 | Factor VIIa inhibitor | PHARMACYCLICS LLC (US) | 2015-11-10 | — | — | US | disclosed |
| US-20140221667-A1 | FACTOR VIIA INHIBITOR | PHARMACYCLICS, INC. (US) | 2014-08-07 | — | — | US | disclosed |
| US-8729117-B2 | Factor VIIa inhibitor | PHARMACYCLICS, INC. (US) | 2014-05-20 | — | — | US | disclosed |
| US-20140080879-A1 | FACTOR VIIA INHIBITOR | PHARMACYCLICS, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-8415328-B2 | Factor VIIa inhibitor | PHARMACYCLICS, INC (US) | 2013-04-09 | — | — | US | disclosed |
| US-20110207939-A1 | FACTOR VIIA INHIBITOR | PHARMACYCLICS, INC. (US) | 2011-08-25 | — | — | US | disclosed |
| US-20080275250-A1 | Factor Viia Inhibitor | PHARMACYCLICS, INC. (US) | 2008-11-06 | — | — | US | disclosed |