Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 15/20 | 0.45 |
| ▸ | IARS1 | P41252 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | MARS1 | P56192 | 2/20 | 0.37 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23043076 | 0.97 | NT5E (0.43) | NT5EIARS1EGFRERBB2MARS1 | |
| SCHEMBL23042960 | 0.92 | NT5E (0.51) | NT5EDNPH1 | |
| SCHEMBL23042827 | 0.87 | NT5E (0.47) | NT5EDNPH1 | |
| SCHEMBL23042819 | 0.85 | NT5E (0.47) | NT5EDNPH1 | |
| SCHEMBL23052668 | 0.81 | NT5E (0.42) | NT5E | |
| SCHEMBL23042840 | 0.81 | NT5E (0.42) | NT5E | |
| SCHEMBL23042817 | 0.80 | NT5E (0.54) | NT5E | |
| SCHEMBL23042860 | 0.79 | NT5E (0.43) | NT5E | |
| SCHEMBL23042824 | 0.77 | NT5E (0.42) | NT5E | |
| SCHEMBL23042944 | 0.76 | NT5E (0.54) | NT5EDNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021040356-A1 | C-NUCLEOSIDES, C-NUCLEOTIDES AND THEIR ANALOGS, EQUIVALENTS AND PRODRUGS THEREOF FOR ECTONUCLEOTIDASE INHIBITION | KAINOS MEDICINE, INC. (KR) | 2021-03-04 | — | — | WO | claimed |
| WO-2021040356-A1 | C-NUCLEOSIDES, C-NUCLEOTIDES AND THEIR ANALOGS, EQUIVALENTS AND PRODRUGS THEREOF FOR ECTONUCLEOTIDASE INHIBITION | KAINOS MEDICINE, INC. (KR) | 2021-03-04 | — | — | WO | disclosed |