Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 11/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23042840 | 0.88 | NT5E (0.42) | NT5EADORA1 | |
| SCHEMBL23052668 | 0.88 | NT5E (0.42) | NT5EADORA1 | |
| SCHEMBL23042824 | 0.85 | NT5E (0.42) | NT5E | |
| SCHEMBL23042958 | 0.85 | NT5E (0.41) | NT5EADORA1 | |
| SCHEMBL23043028 | 0.84 | NT5E (0.42) | NT5E | |
| SCHEMBL29396675 | 0.82 | TSHR (0.51) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL22569958 | 0.82 | TSHR (0.51) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL22579704 | 0.82 | TSHR (0.51) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL23042887 | 0.81 | NT5E (0.54) | NT5EADORA3ADORA1TAS1R3TAS1R1 | |
| SCHEMBL23042793 | 0.81 | NT5E (0.54) | NT5EADORA3ADORA1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021040356-A1 | C-NUCLEOSIDES, C-NUCLEOTIDES AND THEIR ANALOGS, EQUIVALENTS AND PRODRUGS THEREOF FOR ECTONUCLEOTIDASE INHIBITION | KAINOS MEDICINE, INC. (KR) | 2021-03-04 | — | — | WO | claimed |
| WO-2021040356-A1 | C-NUCLEOSIDES, C-NUCLEOTIDES AND THEIR ANALOGS, EQUIVALENTS AND PRODRUGS THEREOF FOR ECTONUCLEOTIDASE INHIBITION | KAINOS MEDICINE, INC. (KR) | 2021-03-04 | — | — | WO | disclosed |