Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 9/20 | 0.54 |
| ▸ | ENPP1 | P22413 | 5/20 | 0.54 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23042806 | 0.85 | NT5E (0.52) | NT5EENPP1PLCG1P2RX1P2RX3 | |
| SCHEMBL22579660 | 0.84 | NT5E (0.56) | NT5EENPP1PLCG1 | |
| SCHEMBL23052587 | 0.84 | NT5E (0.49) | NT5EENPP1PLCG1P2RX1P2RX3 | |
| SCHEMBL22579618 | 0.83 | NT5E (0.43) | NT5EENPP1PLCG1 | |
| SCHEMBL23042874 | 0.83 | NT5E (0.52) | NT5EENPP1PLCG1P2RX1P2RX3 | |
| SCHEMBL22579749 | 0.82 | NT5E (0.61) | NT5EP2RX3 | |
| SCHEMBL22579752 | 0.82 | NT5E (0.55) | NT5EENPP1PLCG1 | |
| SCHEMBL25495988 | 0.79 | HIF1A (0.48) | ALDH1A1 | |
| SCHEMBL18490279 | 0.79 | HIF1A (0.48) | ALDH1A1 | |
| SCHEMBL19859909 | 0.79 | HIF1A (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021040356-A1 | C-NUCLEOSIDES, C-NUCLEOTIDES AND THEIR ANALOGS, EQUIVALENTS AND PRODRUGS THEREOF FOR ECTONUCLEOTIDASE INHIBITION | KAINOS MEDICINE, INC. (KR) | 2021-03-04 | — | — | WO | claimed |
| WO-2021040356-A1 | C-NUCLEOSIDES, C-NUCLEOTIDES AND THEIR ANALOGS, EQUIVALENTS AND PRODRUGS THEREOF FOR ECTONUCLEOTIDASE INHIBITION | KAINOS MEDICINE, INC. (KR) | 2021-03-04 | — | — | WO | disclosed |