SCHEMBL23044729

SCHEMBL23044729

COc1ccc(N(c2ccc(OC)cc2)c2ccc3ccccc3c2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.61
CYP2A6 P11509 1/20 0.61
SMN1; SMN2 Q16637 3/20 0.47
LMNA P02545 2/20 0.47
HTT P42858 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PPARG P37231 2/20 0.44
NPC1 O15118 6/20 0.44
RAB9A P51151 6/20 0.44
CASP3 P42574 2/20 0.44
SENP7 Q9BQF6 2/20 0.44
NQO2 P16083 2/20 0.43
CA4 P22748 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13367670 0.96 CYP1A2 (0.57) CYP1A2CYP2A6SMN1; SMN2LMNAHTT
SCHEMBL16344377 0.95 CYP1A2 (0.55) CYP1A2CYP2A6SMN1; SMN2LMNAHTT
SCHEMBL15183851 0.95 CYP1A2 (0.55) CYP1A2CYP2A6SMN1; SMN2LMNAHTT
SCHEMBL12047972 0.93 CYP1A2 (0.53) CYP1A2CYP2A6SMN1; SMN2LMNAHTT
SCHEMBL12412340 0.93 CYP2A6 (0.53) CYP1A2CYP2A6SMN1; SMN2LMNAHTT
SCHEMBL1680166 0.92 CYP1A2 (0.50) CYP1A2CYP2A6LMNATDP1L3MBTL1
SCHEMBL12047823 0.90 CYP1A2 (0.50) CYP1A2CYP2A6SMN1; SMN2LMNAHTT
SCHEMBL12048454 0.89 CYP1A2 (0.49) CYP1A2CYP2A6SMN1; SMN2LMNAHTT
SCHEMBL14515932 0.88 CA1 (0.46) CYP1A2CYP2A6TDP1L3MBTL1NPC1
SCHEMBL20257292 0.87 CYP2A6 (0.53) CYP1A2CYP2A6SMN1; SMN2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021036158-A1 ORGANIC SMALL MOLECULE HOLE INJECTION/TRANSPORT MATERIAL AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 华南理工大学 2021-03-04 WO disclosed
CN-107954884-A High glass-transition temperature hole-injecting material and its preparation and application 华南理工大学 2018-04-24 CN disclosed