⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3617785 | 0.81 | — | — | |
| SCHEMBL29198470 | 0.80 | — | — | |
| SCHEMBL1648363 | 0.78 | — | — | |
| SCHEMBL2223263 | 0.78 | — | — | |
| SCHEMBL7569651 | 0.78 | — | — | |
| SCHEMBL23537782 | 0.77 | — | — | |
| SCHEMBL22188679 | 0.77 | — | — | |
| SCHEMBL21239607 | 0.77 | — | — | |
| SCHEMBL5433597 | 0.77 | — | — | |
| SCHEMBL744087 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110002989-A | A kind of preparation method of the bromo- 2- chlorobenzoic acid of highly selective 5- | 河北合佳医药科技集团股份有限公司 | 2019-07-12 | — | — | CN | claimed |
| CN-105622382-A | Synthesis method of 5-bromo-2-chloro benzoic acid | SUZHOU TIANMA SPECIALTY CHEMICALS CO LTD | 2016-06-01 | — | — | CN | claimed |
| CN-105153137-A | Preparation method of empagliflozin | SHANGHAI INST TECHNOLOGY | 2015-12-16 | — | — | CN | claimed |
| CN-104744227-A | 5-bromine-2-chlorobenzaldehyde preparation method | PORTON FINE CHEMICALS LTD | 2015-07-01 | — | — | CN | claimed |
| CN-104086379-A | Method for synthesizing forxiga intermediate | ANHUI LIANCHUANG PHARMACEUTICAL CHEMISTRY CO LTD | 2014-10-08 | — | — | CN | claimed |
| CN-121737733-A | Method for synthesizing 2-chlorobenzoic acid by diaphragm electrolytic debromination | 浙江工业大学 | 2026-03-27 | — | — | CN | disclosed |
| CN-121629420-A | Method for synthesizing 2-chlorobenzoic acid by diaphragm-free electrochemical debromination | 浙江工业大学 | 2026-03-10 | — | — | CN | disclosed |
| CN-115445242-A | Treatment device and method for dapagliflozin intermediate mother liquor | 浙江工业大学 | 2022-12-09 | — | — | CN | disclosed |
| CN-108084130-B | A kind of preparation method of antidiabetic drug Dapagliflozin | 东南大学 | 2019-09-10 | — | — | CN | disclosed |
| CN-110191879-A | A kind of histone methyltransferase EZH2 inhibitor, preparation method and its medical usage | 恩瑞生物医药科技（上海）有限公司 | 2019-08-30 | — | — | CN | disclosed |
| CN-106458860-B | Pesticidal compositions and methods related thereto | 美国陶氏益农公司 | 2019-07-26 | — | — | CN | disclosed |
| CN-110002989-A | A kind of preparation method of the bromo- 2- chlorobenzoic acid of highly selective 5- | 河北合佳医药科技集团股份有限公司 | 2019-07-12 | — | — | CN | disclosed |
| US-7625949-B2 | Methods for treating retroviral infections | ROCHE PALO ALTO LLC (US) | 2009-12-01 | — | — | US | disclosed |
| WO-2008079218-A1 | PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-03 | — | — | WO | disclosed |
| US-20050239880-A1 | Methods for treating retroviral infections | ROCHE PALO ALTO LLC | 2005-10-27 | — | — | US | disclosed |
| US-20030220360-A1 | Tricyclic fused heterocycle compounds, process for preparing the same and use thereof | NIPPON SUISAN KAISHA, LTD., A JAPAN CORPORATION | 2003-11-27 | — | — | US | disclosed |
| US-20030186944-A1 | Such as 4-(2-(3-dimethylaminobenzoylamino)phenoxy)phthalic acid for treatment/prevention of diabetes; for inhibiting liver glycogen phosphorylase; dietetics | KRISTIANSEN MARIT (DK) | 2003-10-02 | — | — | US | disclosed |
| US-6590118-B1 | Used in treatment of and/or prevention of diabetes, especially non-insulin dependent diabetes (Type 2 diabetes) | NOVO NORDISK A/S (DK) | 2003-07-08 | — | — | US | disclosed |
| EP-1220832-A1 | NOVEL AROMATIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2002-07-10 | — | — | EP | disclosed |
| WO-2001023347-A1 | NOVEL AROMATIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2001-04-05 | — | — | WO | disclosed |