Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 14/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29452838 | 1.00 | MME (0.38) | MMEPRKD1MMEL1MAPK1 | |
| SCHEMBL23052272 | 0.91 | MME (0.36) | MMEPRKD1MMEL1MAPK1 | |
| SCHEMBL28721826 | 0.91 | KMT2A (0.40) | MMEPRKD1 | |
| SCHEMBL23051909 | 0.91 | KMT2A (0.40) | MMEPRKD1 | |
| SCHEMBL23041632 | 0.91 | KMT2A (0.40) | MMEPRKD1 | |
| SCHEMBL23041604 | 0.91 | KMT2A (0.40) | MMEPRKD1 | |
| SCHEMBL23041634 | 0.91 | KMT2A (0.40) | MMEPRKD1 | |
| SCHEMBL23041512 | 0.86 | PRKD1 (0.38) | MMEPRKD1MMEL1 | |
| SCHEMBL23041520 | 0.86 | PRKD1 (0.38) | MMEPRKD1MMEL1 | |
| SCHEMBL23041552 | 0.86 | PRKD1 (0.38) | MMEPRKD1MMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341132-A | Substituted 1, 3-phenylheteroaryl derivatives and their use in the treatment of diseases | 诺华股份有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-114341132-A | Substituted 1, 3-phenylheteroaryl derivatives and their use in the treatment of diseases | 诺华股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| WO-2021038426-A1 | SUBSTITUTED 1,3-PHENYL HETEROARYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-03-04 | — | — | WO | disclosed |