Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | PHGDH | O43175 | 2/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23041654 | 1.00 | POLB (0.38) | POLBTACR3ABCG2CYP1A2CYP2C19 | |
| SCHEMBL23041655 | 1.00 | POLB (0.38) | POLBTACR3ABCG2CYP1A2CYP2C19 | |
| SCHEMBL29452788 | 1.00 | POLB (0.38) | POLBTACR3ABCG2CYP1A2CYP2C19 | |
| SCHEMBL23041653 | 1.00 | POLB (0.38) | POLBTACR3ABCG2CYP1A2CYP2C19 | |
| SCHEMBL23041990 | 0.97 | POLB (0.37) | POLBTACR3ABCG2CYP1A2CYP2C19 | |
| SCHEMBL23041988 | 0.97 | POLB (0.37) | POLBTACR3ABCG2CYP1A2CYP2C19 | |
| SCHEMBL23041684 | 0.94 | POLB (0.35) | POLBTACR3ABCG2CYP1A2CYP2C19 | |
| SCHEMBL23041680 | 0.94 | POLB (0.35) | POLBTACR3ABCG2CYP1A2CYP2C19 | |
| SCHEMBL23041644 | 0.94 | POLB (0.35) | POLBTACR3ABCG2CYP1A2CYP2C19 | |
| SCHEMBL23041645 | 0.94 | POLB (0.35) | POLBTACR3ABCG2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021038426-A1 | SUBSTITUTED 1,3-PHENYL HETEROARYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-03-04 | — | — | WO | disclosed |