Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 4/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23041475 | 0.94 | HTT (0.36) | USP30HTTRAB9AKMT2AKCNK3 | |
| SCHEMBL23041473 | 0.94 | HTT (0.36) | USP30HTTRAB9AKMT2AKCNK3 | |
| SCHEMBL23041555 | 0.91 | MME (0.35) | USP30HTTRAB9AKMT2AKCNK3 | |
| SCHEMBL29452454 | 0.91 | MME (0.35) | USP30HTTRAB9AKMT2AKCNK3 | |
| SCHEMBL23041557 | 0.91 | MME (0.35) | USP30HTTRAB9AKMT2AKCNK3 | |
| SCHEMBL23041944 | 0.90 | MME (0.36) | USP30HTTRAB9AKMT2AKCNK3 | |
| SCHEMBL29452277 | 0.90 | MME (0.36) | USP30HTTRAB9AKMT2AKCNK3 | |
| SCHEMBL23041943 | 0.90 | MME (0.36) | USP30HTTRAB9AKMT2AKCNK3 | |
| SCHEMBL23041644 | 0.87 | POLB (0.35) | HTTRAB9AKMT2AKCNK3MME | |
| SCHEMBL23041643 | 0.87 | POLB (0.35) | HTTRAB9AKMT2AKCNK3MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021038426-A1 | SUBSTITUTED 1,3-PHENYL HETEROARYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-03-04 | — | — | WO | disclosed |