Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 2/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23041555 | 0.93 | MME (0.35) | MMEKCNK3METUSP30PHGDH | |
| SCHEMBL29452454 | 0.93 | MME (0.35) | MMEKCNK3METUSP30PHGDH | |
| SCHEMBL23041557 | 0.93 | MME (0.35) | MMEKCNK3METUSP30PHGDH | |
| SCHEMBL23041436 | 0.92 | MME (0.36) | MMEUSP30PHGDHTRPV4MMEL1 | |
| SCHEMBL23041433 | 0.92 | MME (0.36) | MMEUSP30PHGDHTRPV4MMEL1 | |
| SCHEMBL23041682 | 0.91 | POLB (0.35) | MMEKCNK3MMP13SCN10ACYP1A2 | |
| SCHEMBL23041680 | 0.91 | POLB (0.35) | MMEKCNK3MMP13SCN10ACYP1A2 | |
| SCHEMBL29452809 | 0.91 | POLB (0.35) | MMEKCNK3MMP13SCN10ACYP1A2 | |
| SCHEMBL23041684 | 0.91 | POLB (0.35) | MMEKCNK3MMP13SCN10ACYP1A2 | |
| SCHEMBL23041473 | 0.90 | HTT (0.36) | MMEKCNK3METUSP30PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021038426-A1 | SUBSTITUTED 1,3-PHENYL HETEROARYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-03-04 | — | — | WO | disclosed |