Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28555511 | 0.93 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4THRB | |
| Butane SCHEMBL17350594 | 0.90 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL976374 | 0.82 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4THRB | |
| Butane SCHEMBL17350474 | 0.81 | TSHR (0.48) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL2306357 | 0.80 | TSHR (0.63) | TSHRHPGDALDH1A1CYP3A4THRB | |
| Butane SCHEMBL28052997 | 0.80 | TSHR (0.96) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL29370161 | 0.80 | TSHR (0.80) | TSHRHPGDALDH1A1CYP3A4THRB | |
| Phosphonic Acid SCHEMBL27908749 | 0.78 | TSHR (0.64) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL28298797 | 0.78 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL1331857 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372516-B2 | (Meth)acrylate phosphonic esters as adhesion promoters | BASF SE (DE) | 2013-02-12 | — | — | US | disclosed |
| EP-2350215-A2 | (METH)ACRYLATE PHOSPHONIC ESTERS AS ADHESION PROMOTERS | BASF SE (DE) | 2011-08-03 | — | — | EP | disclosed |
| US-20100112362-A1 | (METH)ACRYLATE PHOSPHONIC ESTERS AS ADHESION PROMOTERS | CIBA CORPORATION (US) | 2010-05-06 | — | — | US | disclosed |
| WO-2010049322-A2 | (METH)ACRYLATE PHOSPHONIC ESTERS AS ADHESION PROMOTERS | BASF SE (DE) | 2010-05-06 | — | — | WO | disclosed |