Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 16/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 6/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23055049 | 0.92 | HDAC1 (0.53) | ALDH1A1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL13950002 | 0.91 | HDAC1 (0.50) | ALDH1A1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL20232415 | 0.85 | HDAC1 (0.69) | MAPTALOX15TDP1HDAC1HDAC2 | |
| SCHEMBL23054956 | 0.84 | HDAC1 (0.53) | HDAC1HDAC2HDAC3NCOR2HDAC8 | |
| SCHEMBL23054882 | 0.82 | HDAC1 (0.70) | HDAC1HDAC2HDAC3NCOR2HDAC8 | |
| SCHEMBL23054900 | 0.80 | HDAC1 (0.58) | HDAC1HDAC2HDAC3NCOR2HDAC8 | |
| SCHEMBL23055053 | 0.80 | HDAC1 (0.48) | ALDH1A1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL14340060 | 0.79 | HDAC1 (0.57) | CYP2C19MTNR1AMTNR1BHDAC1HDAC2 | |
| SCHEMBL23055060 | 0.78 | HDAC1 (0.72) | HDAC1HDAC2HDAC3NCOR2HDAC8 | |
| SCHEMBL23055104 | 0.78 | HDAC1 (0.48) | HDAC1HDAC2HDAC3NCOR2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210060014-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | CERENO SCIENTIFIC AB (SE) | 2021-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210060014-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | HDAC3, HDAC1, HDAC2 | ALDH1A1 3068/4885CYP1A2 3649/4885CYP3A4 2199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.