Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 10/20 | 0.51 |
| ▸ | NPC1 | O15118 | 9/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28007469 | 0.80 | NPSR1 (0.57) | NPSR1KDRKDM4ECYP1A2RAB9A | |
| SCHEMBL11591505 | 0.80 | NPSR1 (0.57) | NPSR1KDRKDM4ECYP1A2RAB9A | |
| SCHEMBL30824513 | 0.80 | NPSR1 (0.57) | NPSR1KDRKDM4ECYP1A2RAB9A | |
| SCHEMBL7033706 | 0.80 | NPSR1 (0.62) | NPSR1KDRKDM4ECYP1A2RAB9A | |
| SCHEMBL128095 | 0.80 | NPSR1 (0.57) | NPSR1KDRKDM4ECYP1A2RAB9A | |
| SCHEMBL11591503 | 0.80 | NPSR1 (0.57) | NPSR1KDRKDM4ECYP1A2RAB9A | |
| Hydrochloric Acid SCHEMBL25250658 | 0.78 | NPSR1 (0.60) | NPSR1KDRKDM4ECYP1A2RAB9A | |
| Hydrochloric Acid SCHEMBL8606417 | 0.78 | NPSR1 (0.60) | NPSR1KDRKDM4ECYP1A2RAB9A | |
| Hydrochloric Acid SCHEMBL2081815 | 0.78 | NPSR1 (0.60) | NPSR1KDRKDM4ECYP1A2RAB9A | |
| SCHEMBL2111139 | 0.78 | KDM4E (0.58) | NPSR1KDRKDM4ECYP1A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021039961-A1 | RING-FUSED PYRAZOLE DERIVATIVE | 大日本住友製薬株式会社 | 2021-03-04 | — | — | WO | disclosed |