Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22251732 | 0.96 | TSHR (0.43) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL21032475 | 0.91 | TSHR (0.43) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL26401138 | 0.84 | TSHR (0.33) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL21778998 | 0.81 | TSHR (0.46) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL23104919 | 0.79 | TSHR (0.44) | TSHRALDH1A1THRB | |
| SCHEMBL12510864 | 0.76 | TSHR (0.46) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL14185125 | 0.73 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL21190228 | 0.73 | TSHR (0.32) | TSHR | |
| SCHEMBL22064599 | 0.72 | TSHR (0.39) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL23979426 | 0.72 | TSHR (0.39) | TSHRHPGDALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210061955-A1 | MALEIMIDE RESIN FILM AND COMPOSITION FOR MALEIMIDE RESIN FILM | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-03-04 | — | — | US | disclosed |