Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.65 |
| ▸ | AXL | P30530 | 2/20 | 0.63 |
| ▸ | MERTK | Q12866 | 2/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL14736732 | 1.00 | PIK3CD (0.65) | PIK3CDAXLMERTKKCNH2 | |
| SCHEMBL14736930 | 0.93 | PIK3CD (0.71) | PIK3CDAXLMERTKKCNH2 | |
| SCHEMBL31441214 | 0.93 | PIK3CD (0.71) | PIK3CDAXLMERTKKCNH2 | |
| SCHEMBL29836072 | 0.93 | PIK3CD (0.71) | PIK3CDAXLMERTKKCNH2 | |
| SCHEMBL19639739 | 0.93 | PIK3CD (0.71) | PIK3CDAXLMERTKKCNH2 | |
| SCHEMBL14752106 | 0.93 | PIK3CD (0.71) | PIK3CDAXLMERTKKCNH2 | |
| Trifluoroacetic Acid SCHEMBL23065009 | 0.91 | PIK3CD (0.65) | PIK3CDKCNH2 | |
| Trifluoroacetic Acid SCHEMBL14736623 | 0.91 | PIK3CD (0.65) | PIK3CDAXLMERTKKCNH2 | |
| Trifluoroacetic Acid SCHEMBL14736642 | 0.91 | PIK3CD (0.65) | PIK3CDKCNH2 | |
| Trifluoroacetic Acid SCHEMBL14736456 | 0.91 | PIK3CD (0.66) | PIK3CDKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4233869-A2 | USE OF PYRAZOLOPYRIMIDINE DERIVATIVES FOR THE TREATMENT OF PI3K RELATED DISORDERS | Incyte Holdings Corporation (US) | 2023-08-30 | — | — | EP | disclosed |
| EP-3513793-B1 | HETEROCYCLYLAMINES AS PI3K INHIBITORS | INCYTE HOLDINGS CORP (US) | 2021-03-10 | — | — | EP | disclosed |