SCHEMBL23067652

SCHEMBL23067652

Cc1cc(N=C=O)c(N=C=O)c(C)c1N=C=O.Cc1cc(N=C=O)c(N=C=O)c(N=C=O)c1C

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.41
TRPA1 O75762 1/20 0.41
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4298726 0.93 CYP3A4 (0.47) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL3685073 0.93 CYP3A4 (0.47) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL7592953 0.85 CYP3A4 (0.47) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL5576975 0.83 CYP3A4 (0.47) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL2341640 0.81 CYP3A4 (0.47) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL1712846 0.81 CYP3A4 (0.47) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL3677882 0.81 CYP3A4 (0.47) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL1869910 0.81 CYP3A4 (0.40) CYP3A4TRPA1GABRA1GABRB2
SCHEMBL441816 0.80 CYP3A4 (0.43) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL5576972 0.79 CYP3A4 (0.48) CYP3A4TRPA1ALDH1A1HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210071032-A1 ACTINIC RADIATION-CURABLE URETHANE/UREA-CONTAINING AEROSPACE COATINGS AND SEALANTS PRC-DESOTO INTERNATIONAL, INC. 2021-03-11 US disclosed