Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.52 |
| ▸ | RXRB | P28702 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808162 | 0.90 | MAOB (0.71) | MAPTMAOBPARP10KMT2ALMNA | |
| SCHEMBL9574756 | 0.89 | KMT2A (0.71) | MAPTMAOBPARP10SLC6A2SLC6A3 | |
| SCHEMBL50807 | 0.87 | KMT2A (0.73) | MAPTMAOBPARP10SLC6A2SLC6A3 | |
| SCHEMBL1944115 | 0.86 | KMT2A (0.77) | MAPTMAOBPARP10SLC6A2SLC6A3 | |
| SCHEMBL6057219 | 0.86 | KMT2A (0.76) | MAPTSLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL10930442 | 0.85 | KMT2A (0.65) | MAPTMAOBSLC6A2SLC6A3KMT2A | |
| SCHEMBL8333346 | 0.84 | NR4A1 (0.66) | MAOBPARP10SLC6A2SLC6A3LMNA | |
| SCHEMBL17212838 | 0.83 | KMT2A (0.63) | MAPTPARP10SLC6A2SLC6A3KMT2A | |
| SCHEMBL13612596 | 0.83 | MAOB (0.63) | MAPTMAOBPARP10LMNANR4A1 | |
| SCHEMBL8638975 | 0.83 | MAOB (0.63) | MAPTMAOBPARP10LMNANR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11781029-B2 | Heat-sensitive recording material | PAPIERFABRIK AUGUST KOEHLER SE (DE) | 2023-10-10 | — | — | US | disclosed |
| US-11673859-B2 | Polymorphic forms of N-(4-((4-(3-phenylureido)phenyl)sulfonyl)phenyl)benzolsulfonamide | KOEHLER PAPER SE (DE) | 2023-06-13 | — | — | US | disclosed |
| US-20220363629-A1 | POLYMORPHIC FORMS OF N-(4-((4-(3-PHENYLUREIDO)PHENYL)SULFONYL)PHENYL)BENZOLSULFONAMIDE | KOEHLER PAPER SE (DE) | 2022-11-17 | — | — | US | disclosed |
| US-20210071025-A1 | HEAT-SENSITIVE RECORDING MATERIAL | PAPIERFABRIK AUGUST KOEHLER SE (DE) | 2021-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11673859-B2 | Polymorphic forms of N-(4-((4-(3-phenylureido)phenyl)sulfonyl)phenyl)benzolsulfonamide | SCN9A, SCN2A, SCN8A | MAPT 3656/4885MAOB 2695/4885PARP10 2264/4885 |
| US-20220363629-A1 | POLYMORPHIC FORMS OF N-(4-((4-(3-PHENYLUREIDO)PHENYL)SULFONYL)PHENYL)BENZOLSULFONAMIDE | SCN9A, SCN2A, SCN8A | MAPT 3656/4885MAOB 2695/4885PARP10 2264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.