Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1657244 | 0.88 | BUB1 (0.35) | BUB1 | |
| SCHEMBL2598644 | 0.88 | BUB1 (0.35) | BUB1 | |
| SCHEMBL1657246 | 0.88 | BUB1 (0.35) | BUB1 | |
| SCHEMBL6159950 | 0.73 | BUB1 (0.32) | BUB1 | |
| SCHEMBL20660395 | 0.73 | BUB1 (0.34) | BUB1 | |
| SCHEMBL31513965 | 0.73 | BUB1 (0.34) | BUB1 | |
| SCHEMBL3999602 | 0.72 | CRBN (0.40) | BUB1 | |
| SCHEMBL11090872 | 0.71 | PDE4A (0.37) | GAA | |
| SCHEMBL1852888 | 0.71 | PDE4A (0.37) | GAA | |
| SCHEMBL11090868 | 0.71 | PDE4A (0.37) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021042890-A1 | HETEROCYCLIC COMPOUND AND APPLICATION THEREOF AS TRK KINASE INHIBITOR | 罗欣药业(上海)有限公司 | 2021-03-11 | — | — | WO | disclosed |