Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 19/20 | 0.48 |
| ▸ | BAZ2A | Q9UIF9 | 6/20 | 0.48 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23073025 | 0.90 | BRD4 (0.49) | BRD4BAZ2ATLR4TLR9TLR8 | |
| SCHEMBL23073143 | 0.89 | GRIN1 (0.39) | BRD4BAZ2A | |
| SCHEMBL20158761 | 0.88 | BRD4 (0.54) | BRD4BAZ2ATLR4TLR9TLR8 | |
| SCHEMBL18152904 | 0.83 | BRD4 (0.48) | BRD4BAZ2ATLR4TLR9TLR8 | |
| SCHEMBL23073056 | 0.82 | BRD4 (0.48) | BRD4BAZ2ATLR4TLR9TLR8 | |
| SCHEMBL23072950 | 0.82 | BRD4 (0.47) | BRD4BAZ2ATLR4TLR9TLR8 | |
| SCHEMBL18152807 | 0.81 | BRD4 (0.48) | BRD4BAZ2ATLR4TLR9TLR8 | |
| SCHEMBL23073148 | 0.81 | BRD4 (0.46) | BRD4BAZ2ATLR4TLR9TLR8 | |
| SCHEMBL23473037 | 0.80 | BRD4 (0.48) | BRD4BAZ2ATLR4TLR9TLR8 | |
| SCHEMBL18538421 | 0.80 | BRD4 (0.50) | BRD4BAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831383-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| EP-3283077-B1 | BROMODOMAIN INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2021-03-10 | — | — | EP | disclosed |