SCHEMBL23073072

SCHEMBL23073072

Cc1cc(-c2cc(NC=O)c3c(F)nn(Cc4ccc(F)cc4)c3c2)cn(C)c1=O

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 20/20 0.49
BRD9 Q9H8M2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18152720 0.87 BRD4 (0.47) BRD4
SCHEMBL23473025 0.86 BRD4 (0.49) BRD4BRD9
SCHEMBL18152634 0.86 BRD4 (0.54) BRD4
SCHEMBL18152713 0.85 BRD4 (0.46) BRD4BRD9
SCHEMBL18164309 0.81 BRD4 (0.44) BRD4BRD9
SCHEMBL18152749 0.80 BRD4 (0.53) BRD4
SCHEMBL18164276 0.80 BRD4 (0.47) BRD4
SCHEMBL23073066 0.79 BRD4 (0.49) BRD4BRD9
SCHEMBL18152698 0.79 BRD4 (0.63) BRD4
SCHEMBL23072972 0.78 BRD4 (0.45) BRD4BRD9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283077-B1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RES INC (US) 2021-03-10 EP disclosed