Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 15/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18152863 | 0.84 | BRD4 (0.50) | BRD4ALDH1A1TDP1LMNACREBBP | |
| SCHEMBL20158760 | 0.82 | BRD4 (0.47) | BRD4ALDH1A1TDP1LMNABRD9 | |
| SCHEMBL23073011 | 0.81 | BRD4 (0.42) | BRD4 | |
| SCHEMBL23073006 | 0.81 | BRD4 (0.50) | BRD4 | |
| SCHEMBL18164538 | 0.76 | BRD4 (0.42) | BRD4ALDH1A1TDP1LMNABRD9 | |
| SCHEMBL23473023 | 0.75 | BRD4 (0.63) | BRD4 | |
| SCHEMBL23473064 | 0.73 | BRD4 (0.45) | BRD4CREBBPTLR4TLR9TLR8 | |
| SCHEMBL18542060 | 0.73 | BRD4 (0.41) | BRD4ALDH1A1LMNA | |
| SCHEMBL23072951 | 0.72 | BRD4 (0.61) | BRD4 | |
| SCHEMBL23072940 | 0.72 | BRD4 (0.61) | BRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283077-B1 | BROMODOMAIN INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2021-03-10 | — | — | EP | disclosed |