Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 14/20 | 0.36 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 5/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23073148 | 0.89 | BRD4 (0.46) | BRD4BAZ2A | |
| SCHEMBL18538435 | 0.85 | BRD4 (0.45) | BRD4BAZ2AGRIN1GRIN2BBRD9 | |
| SCHEMBL23073049 | 0.83 | BRD4 (0.43) | BRD4 | |
| SCHEMBL18152741 | 0.83 | CNR2 (0.39) | BRD4BAZ2AGRIN1GRIN2BBRD9 | |
| SCHEMBL23073143 | 0.82 | GRIN1 (0.39) | BRD4BAZ2AGRIN1GRIN2BBRD9 | |
| SCHEMBL23473037 | 0.80 | BRD4 (0.48) | BRD4BAZ2A | |
| SCHEMBL18541952 | 0.79 | BRD4 (0.51) | BRD4BAZ2AGRIN1GRIN2BBRD9 | |
| SCHEMBL18541951 | 0.78 | BRD4 (0.36) | BRD4BAZ2AGRIN1GRIN2BBRD9 | |
| SCHEMBL20158761 | 0.75 | BRD4 (0.54) | BRD4BAZ2A | |
| SCHEMBL23073061 | 0.75 | MAP3K11 (0.35) | BRD4BAZ2AGRIN1GRIN2BBRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283077-B1 | BROMODOMAIN INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2021-03-10 | — | — | EP | disclosed |