Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 17/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23072969 | 0.89 | BRD4 (0.38) | BRD4 | |
| SCHEMBL23473105 | 0.86 | BRD4 (0.46) | BRD4TLR4TLR9TLR8TLR7 | |
| SCHEMBL23473064 | 0.85 | BRD4 (0.45) | BRD4CREBBPTLR4TLR9TLR8 | |
| SCHEMBL23073134 | 0.85 | BRD4 (0.52) | BRD4 | |
| SCHEMBL18152877 | 0.84 | BRD4 (0.44) | BRD4CREBBP | |
| SCHEMBL18538415 | 0.84 | BRD4 (0.52) | BRD4CREBBP | |
| Hydrochloric Acid SCHEMBL18152805 | 0.83 | BRD4 (0.43) | BRD4CREBBP | |
| SCHEMBL18164198 | 0.83 | BRD4 (0.47) | BRD4 | |
| SCHEMBL23073126 | 0.83 | BRD4 (0.47) | BRD4 | |
| SCHEMBL23072991 | 0.81 | BRD4 (0.47) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283077-B1 | BROMODOMAIN INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2021-03-10 | — | — | EP | disclosed |