Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 19/20 | 0.44 |
| ▸ | BAZ2A | Q9UIF9 | 5/20 | 0.44 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23073269 | 0.91 | BRD4 (0.45) | BRD4BAZ2ATLR4TLR9TLR8 | |
| SCHEMBL23073213 | 0.90 | GRIN1 (0.35) | BRD4BAZ2A | |
| SCHEMBL23073056 | 0.87 | BRD4 (0.48) | BRD4BAZ2ATLR4TLR9TLR8 | |
| SCHEMBL18152682 | 0.87 | BRD4 (0.43) | BRD4BAZ2ATLR4TLR9TLR8 | |
| SCHEMBL23072961 | 0.85 | BRD4 (0.43) | BRD4BAZ2ATLR4TLR9TLR8 | |
| SCHEMBL23473075 | 0.82 | GRIN1 (0.35) | BRD4BAZ2A | |
| SCHEMBL18152857 | 0.81 | BRD4 (0.43) | BRD4BAZ2A | |
| SCHEMBL23072960 | 0.80 | BRD4 (0.42) | BRD4BAZ2ATLR4TLR9TLR8 | |
| SCHEMBL18152790 | 0.78 | BRD4 (0.44) | BRD4BAZ2A | |
| SCHEMBL23073274 | 0.77 | GRM2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831383-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| EP-3283077-B1 | BROMODOMAIN INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2021-03-10 | — | — | EP | disclosed |