Delta9-Tetrahydrocannabinolic Acid A

Delta9-Tetrahydrocannabinolic Acid A

SCHEMBL23076463

CCCCCc1cc2c(c(O)c1C(=O)O)[C@@H]1C=C(C)CC[C@@H]1C(C)(C)O2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 18/20 1.00
▸ CNR1 P21554 10/20 1.00
▸ LDHA P00338 2/20 1.00
▸ TRPM8 Q7Z2W7 2/20 1.00
▸ DAGLA Q9Y4D2 2/20 1.00
▸ PPARG P37231 1/20 1.00
▸ ABHD12 Q8N2K0 3/20 0.64
▸ ABHD6 Q9BV23 3/20 0.64
▸ FAAH O00519 2/20 0.64
▸ NR1I2 O75469 1/20 0.64
▸ GLRA1 P23415 1/20 0.64
▸ GPR183 P32249 1/20 0.64
▸ DRD3 P35462 1/20 0.64
▸ ENPP2 Q13822 1/20 0.64
▸ GPR18 Q14330 1/20 0.64
▸ GPR55 Q9Y2T6 1/20 0.64
▸ NAAA Q02083 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Delta9-Tetrahydrocannabinolic Acid A SCHEMBL6856735 1.00 CNR2 (1.00) CNR2CNR1LDHATRPM8DAGLA
Delta9-Tetrahydrocannabinolic Acid A SCHEMBL18095976 1.00 CNR2 (1.00) CNR2CNR1LDHATRPM8DAGLA
Delta9-Tetrahydrocannabinolic Acid A SCHEMBL16769847 1.00 CNR2 (1.00) CNR2CNR1LDHATRPM8DAGLA
Delta9-Tetrahydrocannabinolic Acid A SCHEMBL14773902 1.00 CNR2 (1.00) CNR2CNR1LDHATRPM8DAGLA
Delta9-Tetrahydrocannabinolic Acid A SCHEMBL29691633 1.00 CNR2 (1.00) CNR2CNR1LDHATRPM8DAGLA
Delta9-Tetrahydrocannabinolic Acid A SCHEMBL29610699 1.00 CNR2 (1.00) CNR2CNR1LDHATRPM8DAGLA
SCHEMBL25215172 0.99 CNR2 (0.98) CNR2CNR1LDHATRPM8DAGLA
SCHEMBL23121713 0.99 CNR2 (0.98) CNR2CNR1LDHATRPM8DAGLA
SCHEMBL22691773 0.99 CNR2 (0.98) CNR2CNR1LDHATRPM8DAGLA
SCHEMBL23874170 0.99 CNR2 (0.98) CNR2CNR1LDHATRPM8DAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026392-A1 BIOSYNTHESIS OF CANNABINOIDS AND CANNABINOID PRECURSORS GINKGO BIOWORKS, INC. (US) 2024-01-25 — — US disclosed
US-20230340446-A1 BIOSYNTHESIS OF CANNABINOIDS AND CANNABINOID PRECURSORS GINKGO BIOWORKS, INC. (US) 2023-10-26 — — US disclosed
US-20230137139-A1 BIOSYNTHESIS OF CANNABINOIDS AND CANNABINOID PRECURSORS GINKGO BIOWORKS, INC. (US) 2023-05-04 — — US disclosed
US-20220195472-A1 BIOSYNTHESIS OF CANNABINOIDS AND CANNABINOID PRECURSORS GINKGO BIOWORKS, INC. (US) 2022-06-23 — — US disclosed
US-11274320-B2 Biosynthesis of cannabinoids and cannabinoid precursors GINKGO BIOWORKS, INC. (US) 2022-03-15 — — US disclosed
US-20210071209-A1 BIOSYNTHESIS OF CANNABINOIDS AND CANNABINOID PRECURSORS GINKGO BIOWORKS, INC. (US) 2021-03-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230137139-A1 BIOSYNTHESIS OF CANNABINOIDS AND CANNABINOID PRECURSORS CNR1, CNR2, GGPS1 CNR2 2/4885CNR1 1/4885LDHA 4650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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