⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11312316 | 0.80 | — | — | |
| SCHEMBL2098362 | 0.71 | — | — | |
| SCHEMBL7100546 | 0.67 | — | — | |
| SCHEMBL1504634 | 0.67 | — | — | |
| SCHEMBL6883549 | 0.67 | — | — | |
| SCHEMBL4452490 | 0.64 | — | — | |
| SCHEMBL3189547 | 0.64 | — | — | |
| SCHEMBL1977271 | 0.64 | — | — | |
| SCHEMBL16401932 | 0.62 | — | — | |
| SCHEMBL775960 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110452089-A | The synthetic method of p-chloromethyl styrene | GU XIAOXING | 2019-11-15 | — | — | CN | claimed |
| CN-110452089-A | The synthetic method of p-chloromethyl styrene | GU XIAOXING | 2019-11-15 | — | — | CN | disclosed |
| EP-1836172-B1 | 5-HT7 RECEPTOR ANTAGONISTS | ESTEVE LABOR DR (ES) | 2011-08-03 | — | — | EP | disclosed |
| US-7662862-B2 | 5-HT7 receptor antagonists | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2010-02-16 | — | — | US | disclosed |
| US-20090264458-A1 | 5-HT7 RECEPTOR ANTAGONISTS | JOVER ANTONI TORRENS | 2009-10-22 | — | — | US | disclosed |
| US-7553965-B2 | Central nervous system disorders; compounds are 3-sulfonamidoalkyl 2,2a,4,5-tetrahydro-1H-3-aza-acenaphthylenes | LABORATORIES DEL DR. ESTEVE, S.A. (ES) | 2009-06-30 | — | — | US | disclosed |
| US-20090036480-A1 | 5-Ht7 Receptor Antagonists | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2009-02-05 | — | — | US | disclosed |
| EP-1836172-A1 | 5-HT7 RECEPTOR ANTAGONISTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006069775-A1 | 5-HT7 RECEPTOR ANTAGONISTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-07-06 | — | — | WO | disclosed |
| EP-1676840-A1 | 5-HT7 Receptor antagonists | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-07-05 | — | — | EP | disclosed |
| US-20060142321-A1 | 5-HT7 receptor antagonists | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-06-29 | — | — | US | disclosed |
| US-4945118-A | FLAME RETARDANT | THE DOW CHEMICAL COMPANY (US) | 1990-07-31 | — | — | US | disclosed |
| US-4851559-A | FLAME RETARDANT FOR POLYURETHANE FOAM | THE DOW CHEMICAL COMPANY (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0012338-A1 | Dihydropyridazinones, process for their preparation and therapeutical agents containing them | BASF Aktiengesellschaft (DE) | 1980-06-25 | — | — | EP | disclosed |