Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 19/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 19/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23078768 | 0.96 | PDCD1 (0.57) | PDCD1CD274 | |
| SCHEMBL23078650 | 0.89 | PDCD1 (0.44) | PDCD1CD274 | |
| SCHEMBL23078705 | 0.89 | PDCD1 (0.47) | PDCD1CD274 | |
| SCHEMBL23078499 | 0.87 | PDCD1 (0.46) | PDCD1CD274 | |
| SCHEMBL23078503 | 0.85 | PDCD1 (0.52) | PDCD1CD274 | |
| SCHEMBL23078779 | 0.85 | PDCD1 (0.51) | PDCD1CD274 | |
| SCHEMBL23078645 | 0.85 | CD274 (0.44) | PDCD1CD274 | |
| SCHEMBL23078186 | 0.85 | PDCD1 (0.44) | PDCD1CD274 | |
| SCHEMBL23078357 | 0.84 | PDCD1 (0.44) | PDCD1CD274 | |
| SCHEMBL23078659 | 0.83 | PDCD1 (0.41) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021043116-A1 | BIPHENYL COMPOUNDS, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 中国药科大学 | 2021-03-11 | — | — | WO | disclosed |