Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31257814 | 0.85 | KDM4E (0.64) | KDM4ERECQLCA12CA1CA2 | |
| SCHEMBL29126225 | 0.85 | KDM4E (0.64) | KDM4ERECQLCA12CA1CA2 | |
| SCHEMBL11565434 | 0.82 | KDM4E (0.64) | KDM4ERECQLTGM2CES1CA12 | |
| SCHEMBL23079048 | 0.82 | KDM4E (0.64) | KDM4ERECQLTGM2CES1LRRK2 | |
| SCHEMBL23078990 | 0.82 | KDM4E (0.64) | KDM4ERECQLMEN1KMT2ACA12 | |
| Bentazon SCHEMBL9298926 | 0.78 | KDM4E (1.00) | KDM4ERECQLCA2CA9PKM | |
| Bentazon SCHEMBL29379785 | 0.78 | KDM4E (1.00) | KDM4ERECQLCA2CA9PKM | |
| Bentazon SCHEMBL1150626 | 0.77 | KDM4E (0.97) | KDM4ERECQLCA2CA9PKM | |
| Bentazon SCHEMBL8877198 | 0.77 | KDM4E (0.97) | KDM4ERECQLCA2CA9PKM | |
| Bentazon SCHEMBL7937888 | 0.77 | KDM4E (0.97) | KDM4ERECQLCA2CA9PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021043114-A1 | SUBSTITUTED THIADIAZINONE DIOXIDE AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION, AND APPLICATION THEREFOR | 青岛清原化合物有限公司 | 2021-03-11 | — | — | WO | disclosed |