Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 13/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | OXGR1 | Q96P68 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276117 | 0.89 | SUCNR1 (0.50) | PDE10AKDM4ELMNAMEN1KMT2A | |
| SCHEMBL20517681 | 0.88 | SUCNR1 (0.49) | PDE10AKDM4ELMNAMEN1KMT2A | |
| SCHEMBL3275331 | 0.85 | KDM4E (0.50) | PDE10AKDM4ELMNAMEN1KMT2A | |
| SCHEMBL12895009 | 0.83 | PDE10A (0.49) | PDE10AKDM4ELMNAMEN1KMT2A | |
| SCHEMBL27705784 | 0.81 | PDE10A (0.48) | PDE10AKDM4ELMNAMEN1KMT2A | |
| SCHEMBL28337161 | 0.81 | PDE10A (0.48) | PDE10AKDM4ELMNAMEN1KMT2A | |
| SCHEMBL20156313 | 0.81 | HRH1 (0.50) | PDE10AKDM4ELMNAMEN1KMT2A | |
| SCHEMBL27654114 | 0.80 | PDE10A (0.59) | PDE10AKDM4ELMNAALDH1A1GMNN | |
| SCHEMBL12463786 | 0.80 | KDM4E (0.54) | PDE10AKDM4ELMNAMEN1KMT2A | |
| SCHEMBL25636448 | 0.79 | SUCNR1 (0.45) | PDE10AKDM4ELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116813938-A | Conjugated small molecule modified hydrogel and preparation method thereof | 金陵科技学院 | 2023-09-29 | — | — | CN | claimed |
| CN-116813938-A | Conjugated small molecule modified hydrogel and preparation method thereof | 金陵科技学院 | 2023-09-29 | — | — | CN | disclosed |
| US-20210069337-A1 | INTEGRIN TARGETING LIGANDS AND USES THEREOF | SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT | 2021-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210069337-A1 | INTEGRIN TARGETING LIGANDS AND USES THEREOF | ITGAV, ITGA5, ITGB5 | PDE10A 4639/4885KDM4E 3001/4885LMNA 1394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.