Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK2 | P25098 | 20/20 | 0.86 |
| ▸ | ROCK1 | Q13464 | 17/20 | 0.86 |
| ▸ | GRK5 | P34947 | 14/20 | 0.86 |
| ▸ | GRK1 | Q15835 | 5/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17525399 | 0.93 | GRK2 (1.00) | GRK2ROCK1GRK5GRK1 | |
| SCHEMBL17525422 | 0.91 | GRK2 (1.00) | GRK2ROCK1GRK5GRK1 | |
| SCHEMBL17525424 | 0.88 | GRK2 (1.00) | GRK2ROCK1GRK5GRK1 | |
| SCHEMBL17525411 | 0.88 | GRK2 (1.00) | GRK2ROCK1GRK5GRK1 | |
| SCHEMBL17525400 | 0.88 | GRK2 (1.00) | GRK2ROCK1GRK5GRK1 | |
| SCHEMBL17525384 | 0.88 | GRK2 (1.00) | GRK2ROCK1GRK5GRK1 | |
| SCHEMBL17525387 | 0.87 | GRK2 (1.00) | GRK2ROCK1GRK5GRK1 | |
| SCHEMBL17525425 | 0.87 | GRK2 (1.00) | GRK2ROCK1GRK5GRK1 | |
| SCHEMBL29705818 | 0.87 | GRK2 (1.00) | GRK2ROCK1GRK5GRK1 | |
| SCHEMBL17525423 | 0.87 | GRK2 (1.00) | GRK2ROCK1GRK5GRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230035892-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | FLAGSHIP PIONEERING, INC. | 2023-02-02 | — | — | US | disclosed |
| WO-2021046225-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2021-03-11 | — | — | WO | disclosed |