Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK5 | P34947 | 16/20 | 1.00 |
| ▸ | GRK2 | P25098 | 13/20 | 1.00 |
| ▸ | MET | P08581 | 9/20 | 0.74 |
| ▸ | FLT3 | P36888 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23083860 | 0.91 | GRK5 (1.00) | GRK5GRK2METFLT3 | |
| SCHEMBL23083302 | 0.91 | GRK5 (1.00) | GRK5GRK2METFLT3 | |
| SCHEMBL23083305 | 0.90 | GRK5 (1.00) | GRK5GRK2METFLT3 | |
| SCHEMBL23083921 | 0.88 | GRK5 (1.00) | GRK5GRK2MET | |
| SCHEMBL23083286 | 0.86 | GRK5 (1.00) | GRK5GRK2METFLT3 | |
| SCHEMBL23083859 | 0.84 | GRK5 (1.00) | GRK5GRK2METFLT3 | |
| SCHEMBL13577835 | 0.80 | GRK5 (0.83) | GRK5GRK2METFLT3 | |
| SCHEMBL23083928 | 0.79 | GRK5 (0.89) | GRK5GRK2METFLT3 | |
| SCHEMBL23083283 | 0.79 | GRK5 (1.00) | GRK5GRK2METFLT3 | |
| SCHEMBL13577796 | 0.79 | GRK5 (0.85) | GRK5GRK2METFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230035892-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | FLAGSHIP PIONEERING, INC. | 2023-02-02 | — | — | US | disclosed |
| WO-2021046225-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2021-03-11 | — | — | WO | disclosed |