⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18624719 | 0.91 | — | — | |
| SCHEMBL18642967 | 0.89 | — | — | |
| SCHEMBL27114615 | 0.82 | GRIN2D (0.33) | — | |
| SCHEMBL15447902 | 0.79 | — | — | |
| SCHEMBL22743630 | 0.71 | — | — | |
| SCHEMBL18642975 | 0.71 | SOS1 (0.31) | — | |
| SCHEMBL22743841 | 0.71 | GBA1 (0.31) | — | |
| SCHEMBL18477434 | 0.71 | — | — | |
| SCHEMBL16653850 | 0.71 | — | — | |
| SCHEMBL17721097 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303563-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER | 2023-09-28 | — | — | US | disclosed |
| US-20220242859-A1 | INHIBITORS OF SARM1 | DISARM THERAPEUTICS, INC. | 2022-08-04 | — | — | US | disclosed |
| WO-2021043209-A1 | RET INHIBITOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 广东东阳光药业有限公司 | 2021-03-11 | — | — | WO | disclosed |