Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 20/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.63 |
| ▸ | EGFR | P00533 | 1/20 | 0.63 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23083714 | 0.88 | PTPN11 (0.76) | PTPN11KCNH2EGFRMAPK3MAPK1 | |
| SCHEMBL21154460 | 0.88 | PTPN11 (0.80) | PTPN11KCNH2EGFRMAPK3MAPK1 | |
| SCHEMBL25514482 | 0.88 | PTPN11 (0.76) | PTPN11KCNH2EGFRMAPK3MAPK1 | |
| SCHEMBL24233652 | 0.87 | PTPN11 (0.81) | PTPN11KCNH2EGFRMAPK3MAPK1 | |
| SCHEMBL25514319 | 0.87 | PTPN11 (0.84) | PTPN11KCNH2EGFRMAPK3MAPK1 | |
| SCHEMBL23083930 | 0.85 | PTPN11 (0.72) | PTPN11KCNH2EGFRMAPK3MAPK1 | |
| SCHEMBL23083610 | 0.85 | PTPN11 (0.75) | PTPN11KCNH2EGFRMAPK3MAPK1 | |
| SCHEMBL19785043 | 0.85 | PTPN11 (1.00) | PTPN11KCNH2EGFRMAPK3MAPK1 | |
| SCHEMBL30296025 | 0.85 | PTPN11 (1.00) | PTPN11KCNH2EGFRMAPK3MAPK1 | |
| SCHEMBL23083560 | 0.85 | PTPN11 (0.71) | PTPN11KCNH2EGFRMAPK3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021043077-A1 | SUBSTITUTED PYRAZINE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2021-03-11 | — | — | WO | disclosed |