Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 2/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 11/20 | 0.59 |
| ▸ | EPAS1 | Q99814 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MDH1 | P40925 | 1/20 | 0.46 |
| ▸ | MDH2 | P40926 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418066 | 1.00 | SERPINE1 (0.64) | SERPINE1HIF1AEPAS1MAPTKDM4E | |
| SCHEMBL416528 | 0.95 | SERPINE1 (0.65) | SERPINE1HIF1AEPAS1MAPTKDM4E | |
| SCHEMBL23086146 | 0.91 | HIF1A (0.57) | SERPINE1HIF1AEPAS1MAPTKDM4E | |
| SCHEMBL418638 | 0.91 | HIF1A (0.63) | SERPINE1HIF1AEPAS1MAPTKDM4E | |
| SCHEMBL416752 | 0.89 | HIF1A (0.74) | SERPINE1HIF1AEPAS1RAB9AMDH1 | |
| SCHEMBL458286 | 0.85 | SERPINE1 (0.59) | SERPINE1HIF1AEPAS1RAB9AMDH1 | |
| SCHEMBL419680 | 0.83 | HIF1A (0.54) | SERPINE1HIF1AEPAS1RAB9AMDH1 | |
| SCHEMBL418072 | 0.80 | HIF1A (0.66) | SERPINE1HIF1AEPAS1MDH1MDH2 | |
| SCHEMBL420870 | 0.79 | SERPINE1 (0.66) | SERPINE1HIF1AEPAS1RAB9ANPC1 | |
| SCHEMBL29896966 | 0.79 | SERPINE1 (0.66) | SERPINE1HIF1AEPAS1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607348-B1 | Plasminogen Activator Inhibitor-1 Inhibitor | RENASCIENCE INC (JP) | 2021-03-17 | — | — | EP | disclosed |