Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.44 |
| ▸ | TK1 | P04183 | 2/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | DUT | P33316 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1964547 | 1.00 | CSNK1E (0.44) | CSNK1ETK1ACE2ALDH1A1SPHK1 | |
| SCHEMBL1966482 | 0.95 | CSNK1E (0.48) | CSNK1ETK1ALDH1A1SPHK1PLA2G2A | |
| SCHEMBL1966075 | 0.95 | CSNK1E (0.48) | CSNK1ETK1ALDH1A1SPHK1PLA2G2A | |
| SCHEMBL2311831 | 0.95 | CSNK1E (0.48) | CSNK1ETK1ALDH1A1SPHK1PLA2G2A | |
| SCHEMBL11290300 | 0.95 | CSNK1E (0.48) | CSNK1ETK1ALDH1A1SPHK1PLA2G2A | |
| SCHEMBL1964110 | 0.95 | CSNK1E (0.48) | CSNK1ETK1ALDH1A1SPHK1PLA2G2A | |
| SCHEMBL1965903 | 0.95 | CSNK1E (0.48) | CSNK1ETK1ALDH1A1SPHK1PLA2G2A | |
| SCHEMBL1962165 | 0.95 | CSNK1E (0.48) | CSNK1ETK1ALDH1A1SPHK1PLA2G2A | |
| SCHEMBL11148740 | 0.95 | CSNK1E (0.48) | CSNK1ETK1ALDH1A1SPHK1PLA2G2A | |
| SCHEMBL1963646 | 0.95 | CSNK1E (0.48) | CSNK1ETK1ALDH1A1SPHK1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348866-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | Vascular Biogenics Ltd. (IL) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010052718-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2010-05-14 | — | — | WO | disclosed |