Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 7/20 | 0.65 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.65 |
| ▸ | CRBN | Q96SW2 | 13/20 | 0.53 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26609944 | 0.90 | IKZF2 (0.63) | IKZF2IKZF1CRBNCSNK1A1 | |
| SCHEMBL26610701 | 0.90 | IKZF2 (0.62) | IKZF2IKZF1CRBNCSNK1A1 | |
| SCHEMBL26609233 | 0.89 | IKZF2 (0.62) | IKZF2IKZF1CRBNCSNK1A1 | |
| SCHEMBL26608780 | 0.89 | IKZF2 (0.61) | IKZF2IKZF1CRBNCSNK1A1 | |
| SCHEMBL25010615 | 0.89 | IKZF2 (0.69) | IKZF2IKZF1CRBNCSNK1A1 | |
| SCHEMBL26610743 | 0.88 | IKZF2 (0.61) | IKZF2IKZF1CRBNCSNK1A1 | |
| SCHEMBL23105167 | 0.88 | IKZF2 (0.69) | IKZF2IKZF1CRBN | |
| SCHEMBL26609699 | 0.87 | IKZF2 (0.60) | IKZF2IKZF1CRBNCSNK1A1 | |
| SCHEMBL26609498 | 0.87 | IKZF2 (0.62) | IKZF2IKZF1CRBNCSNK1A1 | |
| SCHEMBL26609818 | 0.87 | IKZF2 (0.60) | IKZF2IKZF1CRBNCSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021051034-A1 | RAS PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2021-03-18 | — | — | WO | disclosed |