Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | SELE | P16581 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23092850 | 0.87 | MEN1 (0.44) | MEN1KMT2AHRH3ICAM1SELE | |
| SCHEMBL1933912 | 0.85 | MEN1 (0.49) | MEN1KMT2AKDM4CCREBBPL3MBTL1 | |
| SCHEMBL23092798 | 0.84 | MEN1 (0.44) | MEN1KMT2AICAM1SELEKDM4C | |
| SCHEMBL21657581 | 0.84 | MEN1 (0.48) | MEN1KMT2AKDM4CCREBBPL3MBTL1 | |
| SCHEMBL18105946 | 0.83 | MEN1 (0.50) | MEN1KMT2AHRH3ICAM1SELE | |
| SCHEMBL18105948 | 0.83 | MEN1 (0.50) | MEN1KMT2AHRH3ICAM1SELE | |
| SCHEMBL18105947 | 0.83 | MEN1 (0.50) | MEN1KMT2AHRH3ICAM1SELE | |
| SCHEMBL18105944 | 0.83 | MEN1 (0.50) | MEN1KMT2AHRH3ICAM1SELE | |
| SCHEMBL18105945 | 0.83 | MEN1 (0.50) | MEN1KMT2AHRH3ICAM1SELE | |
| SCHEMBL27031980 | 0.83 | KDM4C (0.47) | MEN1KMT2AKDM4CL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021051034-A1 | RAS PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2021-03-18 | — | — | WO | disclosed |