Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 4/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 5/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 5/20 | 0.41 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2309533 | 0.94 | SELP (0.46) | SELPSIRT2MEN1ALDH1A1HPGD | |
| SCHEMBL2310195 | 0.89 | TLR4 (0.49) | SELPSSTR4SIRT2TLR4SSTR3 | |
| SCHEMBL2310190 | 0.89 | TLR4 (0.49) | SELPSSTR4SIRT2TLR4SSTR3 | |
| SCHEMBL2309654 | 0.89 | TLR4 (0.44) | SELPTLR4 | |
| SCHEMBL2311952 | 0.88 | TLR4 (0.49) | SELPSIRT2TLR4 | |
| SCHEMBL2311946 | 0.88 | TLR4 (0.49) | SELPSIRT2TLR4 | |
| SCHEMBL2313810 | 0.81 | TLR4 (0.52) | SELPTLR4 | |
| SCHEMBL10961054 | 0.80 | TLR4 (0.58) | SELPSSTR4TLR4SSTR3SSTR5 | |
| SCHEMBL10961052 | 0.80 | TLR4 (0.58) | SELPSSTR4TLR4SSTR3SSTR5 | |
| SCHEMBL2308769 | 0.80 | TLR4 (0.51) | SELPTLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232168-B1 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | ONCOTHYREON INC (US) | 2011-08-03 | — | — | EP | disclosed |
| EP-1232168-A2 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | BIOMIRA, INC. (CA) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001036433-A2 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | BIOMIRA, INC. (CA) | 2001-05-25 | — | — | WO | disclosed |