Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.58 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.56 |
| ▸ | TACR1 | P25103 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MDH2 | P40926 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | MMP14 | P50281 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29400386 | 1.00 | PPARG (0.73) | PPARGKMT2AMEN1HSP90AA1HSP90AB1 | |
| SCHEMBL22892483 | 1.00 | PPARG (0.73) | PPARGKMT2AMEN1HSP90AA1HSP90AB1 | |
| SCHEMBL28715267 | 1.00 | PPARG (0.73) | PPARGKMT2AMEN1HSP90AA1HSP90AB1 | |
| SCHEMBL11682927 | 0.92 | MEN1 (0.80) | PPARGKMT2AMEN1HSP90AA1HSP90AB1 | |
| SCHEMBL27656946 | 0.91 | PPARG (0.72) | PPARGKMT2AMEN1HSP90AA1HSP90AB1 | |
| SCHEMBL27656943 | 0.91 | PPARG (0.72) | PPARGKMT2AMEN1HSP90AA1HSP90AB1 | |
| SCHEMBL27656942 | 0.91 | PPARG (0.75) | PPARGKMT2AMEN1HSP90AA1HSP90AB1 | |
| SCHEMBL27656944 | 0.91 | PPARG (0.75) | PPARGKMT2AMEN1HSP90AA1HSP90AB1 | |
| SCHEMBL22091569 | 0.89 | PPARG (0.72) | PPARGKMT2AMEN1HSP90AA1HSP90AB1 | |
| SCHEMBL22091570 | 0.89 | PPARG (0.72) | PPARGKMT2AMEN1HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114080395-A | Synthesis method of alpha-amanitine and derivatives thereof | 纯生物有机有限公司 | 2022-02-22 | — | — | CN | disclosed |
| EP-3792250-A1 | SYNTHESIS OF ALPHA-AMANITIN AND ITS DERIVATIVES | Pure Bioorganics SIA (LV) | 2021-03-17 | — | — | EP | disclosed |
| WO-2021004973-A1 | SYNTHESIS OF A-AMANITIN AND ITS DERIVATIVES | PURE BIOORGANICS SIA (LV) | 2021-01-14 | — | — | WO | disclosed |