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Sugi Predict / Compounds / SCHEMBL23099348

SCHEMBL23099348

SCHEMBL23099348

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cccc5c(-c6ccc(-c7ccc8c(c7)ncn8-c7ccccc7)cc6)cccc45)cc3)n2)cc1

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ KDR P35968 2/20 0.57
▸ FGFR1 P11362 12/20 0.49
▸ MAPT P10636 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ PTK2B Q14289 1/20 0.47
▸ NPSR1 Q6W5P4 1/20 0.47
▸ HTT P42858 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.44
▸ SRC P12931 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17656036 0.93 KDR (0.53) KDRFGFR1MAPTKMT2APTK2B
SCHEMBL17655829 0.93 KDR (0.53) KDRFGFR1MAPTKMT2APTK2B
SCHEMBL17655958 0.91 KDR (0.55) KDRFGFR1MAPTKMT2APTK2B
SCHEMBL18965400 0.90 KDR (0.54) KDRFGFR1MAPTKMT2APTK2B
SCHEMBL27285256 0.88 KDR (0.63) KDRFGFR1MAPTKMT2APTK2B
SCHEMBL17655886 0.88 KDR (0.50) KDRFGFR1MAPTKMT2APTK2B
SCHEMBL17655920 0.88 KDR (0.50) KDRFGFR1MAPTKMT2APTK2B
SCHEMBL17655940 0.88 KDR (0.50) KDRFGFR1MAPTKMT2APTK2B
SCHEMBL17655827 0.88 KDR (0.50) KDRFGFR1MAPTKMT2APTK2B
SCHEMBL17655980 0.86 KDR (0.61) KDRFGFR1MAPTKMT2APTK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021049840-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2021-03-18 — — WO disclosed