Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29661378 | 0.79 | ADORA2A (0.56) | ADORA2AADORA1AXLMKNK1MKNK2 | |
| SCHEMBL5065955 | 0.79 | ADORA2A (0.56) | ADORA2AADORA1AXLMKNK1MKNK2 | |
| SCHEMBL2876033 | 0.78 | AXL (0.52) | ADORA2AADORA1AXLMKNK1MKNK2 | |
| SCHEMBL31744965 | 0.76 | ADORA2A (0.41) | ADORA2AADORA1AXLMKNK1MKNK2 | |
| SCHEMBL30277827 | 0.76 | ADORA2A (0.50) | ADORA2AADORA1AXLMKNK1MKNK2 | |
| SCHEMBL24170311 | 0.76 | ADORA2A (0.50) | ADORA2AADORA1AXLMKNK1MKNK2 | |
| SCHEMBL9383494 | 0.76 | ADORA2A (0.53) | ADORA2AADORA1AXLMKNK1MKNK2 | |
| Hydrochloric Acid SCHEMBL30277817 | 0.74 | ADORA2A (0.49) | ADORA2AADORA1AXLMKNK1MKNK2 | |
| SCHEMBL29936044 | 0.72 | ADORA2A (0.56) | ADORA2AADORA1AXLMKNK1MKNK2 | |
| SCHEMBL24170309 | 0.72 | ADORA2A (0.56) | ADORA2AADORA1AXLMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2528925-A2 | THIENO[3,2-d]PYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY ON PROTEIN KINASES | Hanmi Science Co., Ltd. (KR) | 2012-12-05 | — | — | EP | disclosed |
| WO-2011093684-A2 | THIENO[3,2-d]PYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY ON PROTEIN KINASES | HANMI HOLDINGS CO., LTD. (KR) | 2011-08-04 | — | — | WO | disclosed |