⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27776077 | 0.97 | TSHR (0.46) | — | |
| SCHEMBL5229468 | 0.90 | TSHR (0.41) | — | |
| SCHEMBL28294126 | 0.88 | TSHR (0.39) | — | |
| SCHEMBL386842 | 0.86 | — | — | |
| SCHEMBL20295616 | 0.86 | — | — | |
| SCHEMBL20295819 | 0.86 | — | — | |
| SCHEMBL28848701 | 0.83 | TSHR (0.44) | — | |
| SCHEMBL7605633 | 0.82 | TSHR (0.48) | — | |
| SCHEMBL11579290 | 0.80 | TSHR (0.46) | — | |
| SCHEMBL11579293 | 0.80 | TSHR (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1056 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112752756-B | Tetrahydro-imidazo [4,5-c ] pyridine derivatives as PD-L1 immunomodulators | 因赛特公司 | 2024-06-25 | — | — | CN | claimed |
| US-20240197888-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2024-06-20 | — | — | US | claimed |
| US-20240174643-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2024-05-30 | — | — | US | claimed |
| CN-117983302-A | Catalyst containing ferrocene PNP ligand for ethylene selective tetramerization and preparation method and application thereof | 华东理工大学 | 2024-05-07 | — | — | CN | claimed |
| EP-4355741-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | Biotheryx, Inc. (US) | 2024-04-24 | — | — | EP | claimed |
| US-20230338389-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | INCYTE CORPORATION | 2023-10-26 | — | — | US | claimed |
| CN-116102553-A | Aromatic condensed ring imine compound, and preparation method and application thereof | 华东理工大学 | 2023-05-12 | — | — | CN | claimed |
| CN-115835908-A | Bicyclic heterocycles as FGFR inhibitors | 因赛特公司 | 2023-03-21 | — | — | CN | claimed |
| US-11607416-B2 | Bicyclic heterocycles as FGFR inhibitors | INCYTE CORPORATION (US) | 2023-03-21 | — | — | US | claimed |
| US-11608337-B2 | Heterocyclic compounds as immunomodulators | INCYTE CORPORATION (US) | 2023-03-21 | — | — | US | claimed |
| EP-0912563-A1 | CINCHONAN BASED CHIRAL SELECTORS FOR SEPARATION OF STEREOISOMERS | Lindner, Wolfgang, Prof. Dr. (AT) | 1999-05-06 | — | — | EP | claimed |
| EP-0779888-B1 | PYRIMIDO [5,4-D]PYRIMIDINES, DRUGS CONTAINING THESE COMPOUNDS, THEIR USE, AND PROCESS FOR PREPARING THEM | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-04-28 | — | — | EP | claimed |
| US-5707989-A | ANTITUMOR AGENTS, INHIBITING SIGNAL TRANSDUCTION MEDIATED BY TYROSINE KINASES | DR. KARL THOMAE GMBH (DE) | 1998-01-13 | — | — | US | claimed |
| WO-1997046557-A1 | CINCHONAN BASED CHIRAL SELECTORS FOR SEPARATION OF STEREOISOMERS | LINDNER WOLFGANG (AT) | 1997-12-11 | — | — | WO | claimed |
| CN-1157619-A | Pyrimido [5-4-d] pyrimidines, drugs containing these compounds, their use and process for preparing them | THOMAE GMBH DR K (DE) | 1997-08-20 | — | — | CN | claimed |
| WO-1995024405-A1 | IMIDAZOLIDIN-2-ONES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND METHOD OF PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1995-09-14 | — | — | WO | claimed |
| EP-0139206-B1 | GAMMA-BUTYROLACTONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND IMMUNOMODULATING COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENTS | MITSUBISHI KASEI CORPORATION (JP) | 1988-07-20 | — | — | EP | claimed |
| US-4540687-A | Antibacterial 6'-(2-amino-2-[4-acyloxyphenyl]acetamido)penicillanoyloxymethyl penicillanate 1,1-dioxide compounds | PFIZER INC. (US) | 1985-09-10 | — | — | US | claimed |
| EP-0074777-A1 | Antibacterial 6-(2-amino-2-(4-acyloxy-phenyl) acetamido) penicillanoyloxymethyl esters | PFIZER INC. (US) | 1983-03-23 | — | — | EP | claimed |
| US-3968102-A | VASODILATOR, ANTICOAGULANT | KOHJIN CO., LTD. (JA) | 1976-07-06 | — | — | US | claimed |