Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ULK1 | O75385 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22890269 | 0.76 | GSK3B (0.46) | GSK3BAXLHTR2AHTR2CHTR2B | |
| SCHEMBL31422750 | 0.76 | GSK3B (0.46) | GSK3BAXLHTR2AHTR2CHTR2B | |
| SCHEMBL25274990 | 0.75 | GSK3B (0.43) | GSK3BAXLHTR2AHTR2CHTR2B | |
| SCHEMBL2471366 | 0.72 | GSK3B (0.47) | GSK3BAXLHTR2AHTR2CHTR2B | |
| SCHEMBL118573 | 0.72 | JAK2 (0.64) | GSK3BAXLHTR2AHTR2CHTR2B | |
| SCHEMBL4004201 | 0.71 | GSK3B (0.51) | GSK3BAXLHTR2AHTR2CHTR2B | |
| SCHEMBL30823749 | 0.70 | GSK3B (0.42) | GSK3BAXLHTR2AHTR2CHTR2B | |
| SCHEMBL3148559 | 0.68 | HTR1D (0.58) | GSK3BAXLJAK2CYP3A4 | |
| SCHEMBL2467763 | 0.67 | JAK2 (0.53) | GSK3BAXLHTR2AHTR2CHTR2B | |
| SCHEMBL7571499 | 0.67 | GSK3B (0.51) | GSK3BAXLHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050688-A1 | COMPOUNDS AND USES THEREOF | X-CHEM, INC. (US) | 2021-03-18 | — | — | WO | disclosed |