⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556308 | 1.00 | — | — | |
| SCHEMBL5178627 | 0.97 | — | — | |
| SCHEMBL27817439 | 0.97 | — | — | |
| Potassium SCHEMBL5178632 | 0.97 | — | — | |
| SCHEMBL5179472 | 0.85 | TDP1 (0.52) | — | |
| Hydrogen Peroxide SCHEMBL15167446 | 0.79 | TSHR (0.52) | — | |
| SCHEMBL128525 | 0.78 | — | — | |
| SCHEMBL58195 | 0.78 | — | — | |
| Methane SCHEMBL7257614 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL28806784 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 589 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461773-B | Preparation method and intermediate of sofosbuvir | 江苏豪森药业集团有限公司 | 2020-12-01 | — | — | CN | claimed |
| CN-105461774-B | Preparation method of sofosbuvir | 江苏豪森药业集团有限公司 | 2020-11-24 | — | — | CN | claimed |
| CN-105461774-A | Preparation method of sofosbuvir | JIANGSU HANSON PHAMA GROUP CO LTD | 2016-04-06 | — | — | CN | claimed |
| CN-105461773-A | Preparation method and intermediate of sofosbuvir | JIANGSU HANSON PHAMA GROUP CO LTD | 2016-04-06 | — | — | CN | claimed |
| US-20150336951-A1 | Process For The Preparation Of A DPP-IV Inhibitor | HOFFMANN-LA ROCHE INC. | 2015-11-26 | — | — | US | claimed |
| US-20140350257-A1 | Process for the Preparation of a DPP-IV Inhibitor | F. HOFFMANN-LA ROCHE AG (CH) | 2014-11-27 | — | — | US | claimed |
| US-20140046066-A1 | PROCESS FOR THE PREPARATION OF DPP-IV INHIBITOR | HOFFMANN-LA ROCHE INC. (US) | 2014-02-13 | — | — | US | claimed |
| CN-101525315-B | Chemical process for extraction of 2-hydroxy pyridine derivatives, 2-hydroxyquinoline, and 2-hydroxybenzothiazole | DU PONT | 2013-12-25 | — | — | CN | claimed |
| CN-101790531-B | Process for the preparation of pyrido [2, 1-alpha] isoquinoline derivatives and polymorphic froms thereof | HOFFMANN LA ROCHE | 2013-06-19 | — | — | CN | claimed |
| US-20120232273-A1 | PROCESS FOR THE PREPARATION OF A DPP-IV INHIBITOR | BROMBERGER ULRIKE (CH) | 2012-09-13 | — | — | US | claimed |
| WO-2002002528-A1 | CHEMICAL PROCESS FOR THE EXTRACTION OF 2-HYDROXY PYRIDINE DERIVATIVES, 2-HYDROXYQUINOLINE, AND 2-HYDROXYBENZOTHIAZOLE | SYNGENTA LIMITED (GB) | 2002-01-10 | — | — | WO | claimed |
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | claimed |
| EP-0958287-A1 | SULFAMIDE-METALLOPROTEASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-11-24 | — | — | EP | claimed |
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | claimed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | claimed |
| WO-1998032748-A1 | SULFAMIDE-METALLOPROTEASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-07-30 | — | — | WO | claimed |
| EP-0139522-B1 | METHOD FOR CONTROLLING TERMITES | THE DOW CHEMICAL COMPANY (US) | 1987-05-20 | — | — | EP | claimed |
| EP-0139522-A1 | Method for controlling termites | THE DOW CHEMICAL COMPANY (US) | 1985-05-02 | — | — | EP | claimed |
| US-4209467-A | COBALT COMPLEX CATALYST | DAICEL LTD. (JP) | 1980-06-24 | — | — | US | claimed |